Mass and Energy

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Quite often, physicists want to study massive, unstable particles that have only a fleeting existence (such as the very massive top quark.) However, all that physicists have around them in the every day world are very low-mass particles. How does one perform this amazing feat of using particles with lesser mass to obtain particles of greater mass?

You know Albert Einstein's famous equation that where E is the energy, m is the mass, and c is the speed of light. Therefore,

Question: When did Einstein write ?